Towards Cardio-Precision medicine.

BRaf signaling principles unveiled by large-scale human mutation analysis with a rapid lentivirus-based gene replacement method.

Rapid advances in genetics are linking mutations on genes to diseases at an exponential rate, yet characterizing the gene-mutation-cell-behavior relationships essential for precision medicine remains a daunting task. More than 350 mutations on small GTPase BRaf are associated with various tumors, and ∼40 mutations are associated with the neurodevelopmental disorder cardio-facio-cutaneous syndro...

Synthetic human leukemia models: towards precision medicine

Letter of Editor-in-Chief

Dear Colleagues and students As Editor-in-Chief of Journal of Cardio-Thoracic Medicine, I would like to dedicate my especial respect and appreciation for your kind regards and consideration to our journal. Fortunately, it is our pleasure to announce that Journal of Cardio-Thoracic Medicine is now indexed in DOAJ and Magiran. Additionally we are expecting to index Journal of Cardio-Thoracic Medi...

Towards personalized medicine..

The Establishment of Integrated Chinese and Western “Precision Medicine”- Modern Medicine towards Complexity Science Age

Since the 21st century, with the development of complexity science and the advancement in computer information technology, there are unprecedented vision and technological means for mankind: the most advanced product of biological evolution on this planet. The success of the Human Genome Project opens up a new way for a more comprehensive understanding of modern medicine and the treatment of hu...